5 Amazing Benefits Of Using Differin Gel (that You Didn't Know About). Dermatologist Dr. Dray explains the skin benefits of using differin gel. I discuss differin gel for hyperpigmentation, age spots, sun damage, rosacea, and sebaceous filaments. #differin #retinol #dermatologist
Differin gel for anti-aging
Does Differin gel stop working?
Differin mistakes to avoid
Differin gel
0:00 What is Differin Gel?
2:04 Differin gel for post-inflammatory hyperpigmentation
5:32 Differin gel for age spots
6:37 Differin gel for sun damage
8:20 Differin gel for rosacea
12:00 Differin gel for sebaceous filaments
13:08 Differin gel in pregnancy
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Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Content provided on this Youtube channel is for informational purposes only. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options. Information on this Youtube channel should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products throughout this video are not to diagnose, treat, cure or prevent disease.

As a mature woman with sensitive skin as I have lupus I have had no issues with using Differin. I love it. I have wasted more money on serums for age spots and this helps way more. Thank you
I have been using differin for almost 4 years now and it’s been the only thing that has helped tremendously with my cystic acne. I’ll never stop using it!
Only thing that worked for mine was a combo of retnoid and winlevi
Same.
wow. i was wondering if differin would help with cystic acne since it’s a more severe kind of acne… that’s really nice to hear. how long did it take to work for you? 😊
I just have to say how your Adapalene application video helped me to transform my skin. Your recommended routine was the only one that worked when starting this, i was really nervous bc of the potential skin purging but it didn’t last too long. Thank you so much Dr. Dray ❤
What’s the name of that vid cuh
Yep, can I just say, thanks to Dr. Drays instructions, I started 0,05 Tretinoin last year, eventually graduating to nightly, and has yet to experience ANY irritation let alone a purge. And my skin has allways been unbelievably fuzzy. So grateful for this Channel and all Andreas sensible and free advice. Thank you!!
Would you mind linking the video you’re referring to? Thanks!
Great timing for this video for me! I just started using Differin. I’ve stayed away from it because I thought it would be too harsh or drying for me, compared to other retinoids. I guess my experience with other topical acne treatments has made me apprehensive. But I’ve been struggling more and more with acne, even though I was using retinal. I’ve only used Differin twice (introducing it slowly), but I haven’t had any adverse effects so far. This video has made me much more confident that I’ll be able to tolerate it and that it may be a great retinoid for me!
I’d love to see more research on the anti-aging effects of adapalene. I understand that it’s more selective in terms of the receptors it affects relative to tretinoin. A head-to-head comparison of anti-aging / photo aging treatment would be interesting to see.
I cover those studies here https://youtu.be/Fr6E3Y3bjUA
@Dr Drayyou are the Best Dr. Dray ❤
@Dr Draythank you for the link.
there is only a tiny amount of research at this stage, but there will be more
It’s funny, I was using Differin Gel and had a lot of irritation, even though I wasn’t even using it everyday and putting on a moisturizer beforehand (and sometimes afterwards). I changed to Tret because I was more interested in anti-aging and was afraid Differin wouldn’t be enough but I was incredibly nervous about the potential of even more irritation. I’ve had ZERO issues with Tretinoin cream .025%. Plus, I find the cream much easier to apply than a gel.
Very helpful and encouraging, thank you! ❤
Thanks for the info Dr Dray.
I’m going to look into differin gel. My rosacea is so much better now that I have a solid skincare routine. Retinoids have been a main component.
My skin looks so much better than it did 10 years ago. Pretty amazing, really.
I was prescribed Differin when it first came out. It’s very good and one of the better over the counter skincare bargains out there. It does help with my sunspots and skin texture too, similar to what Retin A does. I’ve used both.
How does differin compare to tretinoin for anti-aging? https://youtu.be/Fr6E3Y3bjUA
Anecdotally, I’ve used both on and off since the 90’s and think that Differin is comparable in effect to the lowest strength tretinoin. Weak evidence, I know, but thought that might be helpful to someone out there. I’d buy Differin or generic adapalene any day over a cosmetic retinol product for sun spots, fine lines and improving skin texture based on my experience with it.
Dr Dray, since it doesn’t get absorbed much into the body system, do you think it is a safe product to try to remove light pigmentation on the chest near the cleavage of the boobs for mature women?
Hi Dr. I have dry sensitive clear skin but recently see milia. Do I use this on my whole face or only the milia? I love your show! ❤
I trued benzoyl peroxide, salicylic acid, topical spironolactone & clindamycin, you name it and nothing made much of a difference. The FIRST time I used Adapalene my acne cleared about 50% overnight. It’s insane.
that’s so encouraging. did you purge at all? how long have you been using it? 😊
Not my case! Adapalene has not helped me at all.
@Victoria I don’t believe so. I did make the mistake of using it with other actives so it dried my face out and heightened my sensitivity to sun. The tube specifically says not to do that. I stopped using all actives and moisturized for a few days to heal my skin and I now use the Adapalene is a spot treatment when necessary.
Both adapalene and tretinoin are topical retinoids that are effective for treating acne and signs of aging. However, there are some key differences between the two medications.
Adapalene
Adapalene is a third-generation retinoid that is available over-the-counter (OTC) in the United States. It is less irritating than tretinoin and is a good option for people with sensitive skin. Adapalene is effective for treating mild to moderate acne, but it is not as effective as tretinoin for severe acne. Adapalene has also been shown to improve the appearance of fine lines and wrinkles, but it is not as potent as tretinoin for anti-aging.
Tretinoin
Tretinoin is a first-generation retinoid that is available by prescription. It is the most potent retinoid available and is the gold standard for treating acne and signs of aging. Tretinoin is effective for treating all types of acne, including mild, moderate, and severe acne. It is also effective for improving the appearance of fine lines, wrinkles, age spots, and hyperpigmentation. However, tretinoin can be irritating to the skin, especially when first starting out.
Overall, tretinoin is the more effective medication for acne and anti-aging. However, adapalene is a good option for people with sensitive skin or those who are new to retinoids.
Journal of the American Academy of Dermatology
Adapalene Gel 0.1% Versus Tretinoin Gel 0.025% in the Treatment of Acne Vulgaris: A Randomized, Double-Blind, Multi-Center Study
Tretinoin Gel 0.025% Versus Adapalene Gel 0.1% in the Treatment of Facial Acne in Asian Patients: A Randomized, Double-Blind, Multi-Center Study
British Journal of Dermatology
Adapalene and Tretinoin: A Review of Their Comparative Efficacy and Safety in the Treatment of Acne Vulgaris
Adapalene and Tretinoin: A Comparative Review of Their Efficacy and Safety in the Treatment of Photoaging
Journal of Cosmetic and Laser Therapy
Adapalene Versus Tretinoin for the Treatment of Acne Vulgaris: A Review of the Literature
Adapalene and Tretinoin: A Comparative Review of Their Efficacy and Safety in the Treatment of Facial Wrinkles and Fine Lines
Thank you
Thank you for sharing
Do you know if the CVS adapalene is just as good as the differin brand?
@hcapit’s great! I used that after I ran out of differin
0:16: 💡 Adapalene gel is an FDA-approved acne treatment that helps improve how cells behave in the pores, preventing blackheads and inflamed bumps.
3:13: 🎯 Controlling acne is crucial for addressing post-inflammatory hyperpigmentation, and adapalene can help with both.
6:20: 🌞 Adapalene can help lighten H spots on the back of hands, improve sun damage, and reduce the formation of actinic keratosis.
9:59: 💡 Topical treatments for rosacea may work by reducing the burden of mites or addressing the bacteria that live on them, and retinoids can help with reducing papules and pustules.
13:16: 🌟 Adapalene is a retinoid acne treatment that has been around since 1996 and is not significantly absorbed into the body.
Recap by Tammy AI
Thank you for the timeline and time stamps ❤
H spots :D I love that
I just started using differin exactly 3 weeks ago as I was so afraid of purging and have acne on just my cheeks. I’ve suffered with hormonal acne for 10 years now and although it calmed down as I got older, I was still getting deep scarring that takes forever to heal. It is just my luck that after 2 weeks, I’m not really breaking out anymore. I know I can’t really say I’m in the clear until the next 2ish months go by, but I’m super happy right now! I already see my hyperpigmentation fading each day along with consistent sunscreen use <3
I am absolutely OBSESSED with Differin. I’ve been using it for decades. I can’t really tolerate tretinoin. I have rosacea, and tretinoin really tears my face up something terrible. However, Differin actually seems to calm my rosacea and gives me baby soft, smooth, even skin. Now into my 50’s…I have very few very fine lines. I attribute that to my decades of differin use. I used to get it from my derm with an rx. Now I just buy the OTC version. Love it!
I have been using it for at least five years and my skin looks great! I get compliments all the time that I don’t look my age(I am 54). I lived in FL for 10 hrs and had a lot of “freckles” on my face and they are gone now and I know it’s from daily sunscreen but also adapelene.
Thanks Dr Dray for all you do! I save money and keep it simple😊
I started using Differin in April. It’s taken a while but I have not had any breakouts the last few months and my skin texture seems smoother. I have not experienced any irritation or dryness at all but I do use a moisturizer after applying. And my dark marks from previous breakouts are fading. I’ve been pleased so far and will continue to use it. Thanks, as always, Dr Dray. Happy Thursday! I hope you have a lovely evening. 💙
Differin is great! I have been using it for over a year now, and my skin looks amazing! I admit it was very drying at the very beginning, especially around my lips (use vaseline to protect), but it didn’t last longer than a month. Absolutely worth it!
Thank you, Dr Dray :)
hi dr. dray! i would really love to hear your take on acne: hard water vs distilled/soft water. thanks for all your helpful content ❤ edit: also skin and water ph levels in general!
I’ve used Differin regularly for 5+ years. It has done wonders to my skin. Didn’t get rid of acne completely but it is much more under control than before and spots are smaller and not huge bumps as I had before. The biggest improvement has been smoothness and brightness of the skin – it looks flawless now and so soft to touch. It took me long time to get used to it since I have sensitive skin but has been skin changing. Now I am trying isotretinoin topical – I’m finding it way gentler than Differin and was able to use it every day since beginning with no irritation. I’ve also got some tazarotene to try next.
Thanks for the video. I am almost sixty and find that using Adapalene keeps me from having such oily skin. My skin has always been extremely oily (but not acne prone). You would think it would dry with age, but no. Adapalene keeps my skin matte. Love it.