AmLactin + Retinoids: The Anti-Aging Combo That Actually Works

In this video, board-certified dermatologist Dr. Dray breaks down how to use AmLactin and retinoids together to improve the appearance of aging skin, including fine lines, rough texture, and uneven tone.

She explains how lactic acid, an alpha hydroxy acid found in AmLactin lotions, works on the skin as both a chemical exfoliant and a humectant. She also dives into the science behind different concentrations, including why 5% lactic acid mainly provides surface-level exfoliation, while 12% lactic acid can have deeper effects on the skin, including improving dermal thickness and firmness over time.

Dr. Dray clarifies that AmLactin is a brand name with multiple formulations containing different percentages of ammonium lactate, and explains why she typically recommends 12% or higher. She also discusses why a 15% formula is not necessarily more powerful, as formulation differences play a major role in how effective a product is.

The video also covers how retinoids work at a deeper level in the skin to stimulate collagen, improve cell turnover, and target signs of aging and pigmentation. When used appropriately, retinoids and lactic acid can complement each other to enhance skin rejuvenation.

Dr. Dray emphasizes that this combination is best suited for experienced retinoid users and walks through safe ways to incorporate AmLactin into a routine, including alternating use, morning versus evening application, and how to patch test before full use.

She also highlights important safety considerations, including increased sun sensitivity with alpha hydroxy acids, proper sunscreen use, and why facial waxing should be avoided when using these ingredients due to risk of skin injury.

If you are looking to improve skin texture, brightness, and firmness with evidence-based skincare, this video offers a detailed and practical guide.

TIMESTAMPS
0:00 Intro
0:39 What is AmLactin
1:11 5% vs 12% lactic acid
3:10 12% vs 15% clarification
4:16 What retinoids do
6:01 Why combine AmLactin and retinoids
7:50 Who should use this combination
8:55 How to use AmLactin with a retinoid
12:33 Sun sensitivity explained
13:57 Side effects and waxing caution
15:36 Bottom line
16:11 Outro

PRODUCTS MENTIONED
AmLactin Daily Lotion 12%

Adapalene

RELATED VIDEOS
AmLactin Lotion Review

For more dermatologist-backed skincare tips on retinoids, anti-aging, exfoliation, and sensitive skin routines, subscribe to the channel and check out Dr. Dray’s other videos.

FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links.

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Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Content provided on this Youtube channel is for informational purposes only. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options. Information on this Youtube channel should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products throughout this video are not to diagnose, treat, cure or prevent disease.

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90 Comments

    1. Thanks for vids like this.

      My only issue is that I have sensitivities to cones, and all amlactin (lotions and creams) seem to include it. Having psoriasis, along with sensitive uber-dry skin in a semi-arid climate requires me to reduce exposure to many things that irritate my skin, such as castor oil & derivatives (which is worse than cones for my skin,) even at a lower amount. Looking for an alternative that doesn’t break the bank.

    2. What do you suggest I use for creepy skin and 56 and I’m starting to get really creepy skin on my legs and it’s really bothering me. I try everything exfoliating retinoid creams.

  1. There was a study showing that 12% lactic acid applied multiple times a week helped reverse facial skin atrophy caused by overuse of hydrocortisone.

    1. ​@8coolbeans8I have, I think it can help sometimes. Eczema is so multifactorial in what causes and exacerbates it

    2. @Barbara-l4s4oI don’t think that was mentioned in the study but I’m sure it would help with that also though not sure to what degree 👍

  2. For my skin, best thing ever happened to when I lost my job & was broke….and can only afford what is needed. Cerave SA lotion, Adapalene (Walgreen version), Panoxyl 10% BP cleanser, Blackgirl sunscreen, & Vaseline!
    And magic happened! ❤
    All thanks to Dr. Dray! Because of her I started to check the ingredients & was able to figure out what works & what doesn’t for me!!! ❤

  3. I cannot believe you are telling us about this. I have been using this at night (Amlactin and retinoid)all winter and spring at night. I use AMlactin because of your recommendations and it works. My skin looks great at 64 and am fortunate that I do not suffer from any sensitivities.Thank you for all you do!

    1. Omg, I already have Amlactin AND the Gold Bond and NOW I know how to use them together properly. Thank you & SUBSCRIBED👍🏽

    2. Thank you for sharing your experience. Do you apply Amlactin, then retinoid? Do you let it dry or just one right after the other? ❤ Thank you!

  4. ❤❤❤ I’m so thankful for this wealth of FREE information from a credible & credentialed medical professional. ❤❤❤

  5. Amlactin doesn’t get enough love. It helped smooth out my ugly old man hands. The difference is astounding.

    1. At a very young age, I’ve always had old looking hands and I do use lactic acid on my hands. I stopped doing it. I wonder if I use a retinoid on my hands with it. Will it help

  6. Being a rn for over 24 years, no one in my opinion comes close to Dr. Drays knowledge and information that she freely gives to us! Thank you Dr. Dray! She is top tier and I am here for all of it! She should say sunscreen and subscribe and you’re welcome! 😅

    1. I really like Dr Dray, but Lab Muffin, aka Michelle Wong, is the best imo. I’ve learned so much from her.

    2. @lizlemon8035I’m sure this comment is heart warming and appreciated by the content creator on whose video you commented.

    3. @jenwithonen3192 what a dumb, passive aggressive comment. You have a problem with people suggesting other experts to check out? Lab Muffin is probably the most well known and most respected person doing these topics, solely because her knowledge and expertise is unmatched. Enjoy living in your bubble though.

  7. Lmao. When you’ve had skin problems for so long that you look in your medicine cabinet and already have a 12% ammonium lactate cream and tretinoin.

    1. I use it, but didn’t know about Costco (since I send my husband!), thanks. I don’t like the smell, but I think it wears off.

    1. Rip the affordability. Already has nearly doubled in price over the last few years. :(

    2. Yep, and they will raise the price and we won’t be able to afford it again like cerave, it used to be less than 5 bucks and now it’s 15 if not more.

  8. I’ve been using Olay’s retinol with peptides and once it settles in, I follow up with Amlactin 12%. My facial skin has been improving.

    1. Yes, and agree! I lost my 34-career, so focusing on the best affordable options is key. Dr. Dray is the best at this!

  9. I’ve been using the 15% AHA Amlactin for 3 weeks. It’s my only shincare change. One change I never expected is my new robust tolerance of tretinoin. I can usually tolerate 2x per week. I can now apply tretinoin daily with no issues, no redness, no peeling dry skin. I’ve used tret for 3 years now, Amlactin rocks!

    1. ​@bettyboop8264Amlactin both morning and night. At night, I wait until tret has dried down and absorbed, then Amlactin.

  10. I’ve been loving Amlactin for ages. No “luxury” body lotion even comes close. Adding a resinous will be Chef’s kiss!

    1. If he could reach 16,000 people at once instead of explaining it a thousand times to individuals he might

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